The Role of Progranulin (PGRN) in the Pathogenesis of Ischemic Stroke | SpringerLink
Microorganisms | Free Full-Text | Association of Progranulin Gene Expression from Dyspeptic Patients with Virulent Helicobacter pylori Strains; In Vivo Model
Frontiers | Granulin in Frontotemporal Lobar Degeneration: Molecular Mechanisms of the Disease
Progranulin in frontotemporal lobar degeneration and neuroinflammation | Journal of Neuroinflammation | Full Text
Schematic diagram of the progranulin (PGRN) mechanism in HUVECs.... | Download Scientific Diagram
Cells | Free Full-Text | Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases
Progranulin attenuates liver fibrosis by downregulating the inflammatory response | Cell Death & Disease
Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease - eBioMedicine
Progranulin as a therapeutic target in neurodegenerative diseases - ScienceDirect
Progranulin as a therapeutic target in neurodegenerative diseases - ScienceDirect
Gene Mutations and Dementia
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice | EMBO reports
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 | Nature
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis | Nature Communications
Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects - ScienceDirect
Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency - ScienceDirect
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia - ScienceDirect
Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification - Journal of Molecular and Cellular Cardiology
The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases | Science Advances
Outcomes of progranulin gene therapy in the retina are dependent on time and route of delivery: Molecular Therapy - Methods & Clinical Development
Progranulin in neurodegenerative dementia - Wang - 2021 - Journal of Neurochemistry - Wiley Online Library
PGRN mutations identified in FTLD patients. Schematic representation of... | Download Scientific Diagram
![Progranulin [PGRN] - Marker of Neuroinflammation](https://adipogen.com/pub/media/wysiwyg/Landing-Pages/Progranulin/Roles_of_Progranulin.PNG "Progranulin [PGRN] - Marker of Neuroinflammation")
Progranulin [PGRN] - Marker of Neuroinflammation
Progranulin deficiency leads to reduced glucocerebrosidase activity | PLOS ONE
PGRN interactions, trafficking, and proteolysis. Several PGRN receptors... | Download Scientific Diagram
